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SRX9285313: GSM4829722: Apc Kras sample 3; Mus musculus; RNA-Seq
1 ILLUMINA (NextSeq 500) run: 35M spots, 2.5G bases, 976.9Mb downloads

Submitted by: NCBI (GEO)
Study: Transcriptional profiling of intestinal changes in Apc Kras tumours with MYC activation and/or drug combination treatment
show Abstracthide Abstract
Transcriptional profiling of intestinal changes in Apc Kras tumours with MYC activation and/or drug combination treatment Overall design: Apc Kras or Apc Kras MYC mice were treated with or without a eFT508/rapamycin drug combination, then whole intestines were extracted and transcriptomic analysis performed to investigate changes occuring with MYC and/or drug treatment.
Sample: Apc Kras sample 3
SAMN16427555 • SRS7512822 • All experiments • All runs
Organism: Mus musculus
Library:
Instrument: NextSeq 500
Strategy: RNA-Seq
Source: TRANSCRIPTOMIC
Selection: cDNA
Layout: PAIRED
Construction protocol: 1cm of proximal intestine was collected and dissociated using Precyllis homogeniser in b-ME in RLT buffer. RNA was extracted using Qiagen RNA extraction kit following manufacturer's instructions. Libraries for cluster generation and DNA sequencing were prepared following a previously described method (Fisher et al. 2011) using TruSeq RNA sample prep kit v2 (Illumina) The libraries were run on Illumina Next Seq using the High Output 75 cycles kit (2x36 cycles, paired end reads, single index)
Experiment attributes:
GEO Accession: GSM4829722
Links:
Runs: 1 run, 35M spots, 2.5G bases, 976.9Mb
Run# of Spots# of BasesSizePublished
SRR1281723934,986,3482.5G976.9Mb2021-01-02

ID:
12114002

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